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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
11.5 DPC

25 matching records from 25 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Msx2  msh homeobox 2   (Synonyms: Hox8, Hox-8, Hox8.1)
Results  Reference
1J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99
1*J:173512 Boogerd CJ, Moorman AF, Barnett P, Expression of muscle segment homeobox genes in the developing myocardium. Anat Rec (Hoboken). 2010 Jun;293(6):998-1001
1J:161903 Boogerd KJ, Wong LY, Christoffels VM, Klarenbeek M, Ruijter JM, Moorman AF, Barnett P, Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43. Cardiovasc Res. 2008 Jun 1;78(3):485-93
1J:139946 Chen YH, Ishii M, Sucov HM, Maxson RE Jr, Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium. BMC Dev Biol. 2008;8:75
1J:124119 Chen YH, Ishii M, Sun J, Sucov HM, Maxson RE Jr, Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract. Dev Biol. 2007 Aug 15;308(2):421-37
1J:221100 Choi KS, Lee C, Maatouk DM, Harfe BD, Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth. PLoS One. 2012;7(5):e37826
1J:291919 Darrigrand JF, Valente M, Comai G, Martinez P, Petit M, Nishinakamura R, Osorio DS, Renault G, Marchiol C, Ribes V, Cadot B, Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation. Elife. 2020 Feb 27;9:e50325
1J:75084 Gaussin V, Van de Putte T, Mishina Y, Hanks MC, Zwijsen A, Huylebroeck D, Behringer RR, Schneider MD, Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2878-83
1*J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50
1J:229313 Goodnough LH, Dinuoscio GJ, Atit RP, Twist1 contributes to cranial bone initiation and dermal condensation by maintaining wnt signaling responsiveness. Dev Dyn. 2016 Feb;245(2):144-56
1J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73
1J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
1*J:41811 Lanctot C, Lamolet B, Drouin J, The bicoid-related homeoprotein Ptx1 defines the most anterior domain of the embryo and differentiates posterior from anterior lateral mesoderm. Development. 1997 Jul;124(14):2807-17
1J:206314 Misra K, Luo H, Li S, Matise M, Xiang M, Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFbeta signaling to specify V2b interneurons in the spinal cord. Development. 2014 Jan;141(1):187-98
1*J:11525 Monaghan AP, Davidson DR, Sime C, Graham E, Baldock R, Bhattacharya SS, Hill RE, The Msh-like homeobox genes define domains in the developing vertebrate eye. Development. 1991 Aug;112(4):1053-61
1J:308270 Moon KH, Ma JH, Min H, Koo H, Kim H, Ko HW, Bok J, Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models. Elife. 2020 Dec 31;9:e56551
1J:299544 Nakatomi M, Ludwig KU, Knapp M, Kist R, Lisgo S, Ohshima H, Mangold E, Peters H, Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development. Development. 2020 Jun 24;147(21):dev189175
1J:283382 Qin L, Ahn KJ, Wine Lee L, de Charleroy C Jr, Crenshaw EB 3rd, Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip. PLoS One. 2019;14(12):e0226602
1J:119303 Seo S, Kume T, Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract. Dev Biol. 2006 Aug 15;296(2):421-36
1*J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1*J:33667 Takahashi Y, Organization of the spina bifida neural tube in Splotch (Pax-3 defective) mouse embryos. Dev Growth Differ. 1996 FEB;38(1):23-31
1J:300455 Vu TH, Takechi M, Shimizu M, Kitazawa T, Higashiyama H, Iwase A, Kurihara H, Iseki S, Dlx5-augmentation in neural crest cells reveals early development and differentiation potential of mouse apical head mesenchyme. Sci Rep. 2021 Jan 22;11(1):2092
1*J:90386 Wang CK, Omi M, Ferrari D, Cheng HC, Lizarraga G, Chin HJ, Upholt WB, Dealy CN, Kosher RA, Function of BMPs in the apical ectoderm of the developing mouse limb. Dev Biol. 2004 May 1;269(1):109-22
1J:266477 Wang Y, Lu P, Wu B, Riascos-Bernal DF, Sibinga NES, Valenta T, Basler K, Zhou B, Myocardial beta-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation. J Mol Cell Cardiol. 2018 Sep 8;123:150-158
1J:184697 Zhao J, Kawai K, Wang H, Wu D, Wang M, Yue Z, Zhang J, Liu YH, Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly. Am J Pathol. 2012 Jun;180(6):2230-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory